News

27 December 2023 – Dhiman and Zach’s paper on the synthesis of functionalized hexahydrocarbazoles has been published in Organic Letters! [link]

21 April 2023 – Zach and Leah’s paper on regiodivergent (3+2) annulation reactions of oxyallyl cations has been accepted for publication in Chemical Science! [link]

26 August 2022 (this position has been filled)Applications are invited for a fully funded postdoctoral position in the Wu research group in the Department of Chemistry at Dartmouth College.  The person in this position will be involved in the development of new chemical methodology in organic chemistry and the total synthesis of indoline alkaloid natural products.  The preferred start date is as soon as possible but is flexible.  The starting salary for this position will be $54,840 per year + benefits.

Applicants for this position must hold a PhD in organic chemistry and have experience in multi-step synthesis.

To apply, please submit the following materials via email to jimmy.wu@dartmouth.edu

  1. Research Summary of graduate work and post-graduate work (if any)
  2. CV, including the names of three individuals who can provide letters of recommendation (one of these names must be your PhD advisor)

Review of applications will begin immediately and continue until the position is filled.  Questions regarding this position should be directed to Prof. Jimmy Wu (jimmy.wu@dartmouth.edu).

Dartmouth College is an equal opportunity/affirmative action employer with a strong commitment to diversity and inclusion. We prohibit discrimination on the basis of sex, race, color, religion, age, disability, status as a veteran, national or ethnic origin, sexual orientation, gender identity, gender expression, or any other category protected by applicable law, in the administration of its educational policies, admission policies, scholarship and loan programs, employment, or other school administered programs. Applications by members of all underrepresented groups are encouraged. Details of employment conditions at Dartmouth College will be provided at the time of offer.

25 August 2022 – Our NIH R01 was funded today for the next 4 years!  Thank you NIGMS and all the talented people in the research group for making this possible.

01 July 2021 – Jimmy Wu is promoted to Full Professor.

12 August 2020 – Congrats to Leah and Mathes on their recent collaborative publication with Houk and Liu regarding the diversification of NuBFr products! [link]

06 August 2020 – Our latest animation on natural products-inspired drugs has just been posted to the outreach tab on our website [link]!  Thanks to NSF for funding this project!

15 July 2019 – Sam, Evan, and Leah’s paper on nucleophile-intercepted Beckmannn fragmentations just published in Chemical Science! [link]

01 July 2019 – Our latest NSF grant is funded (CHE-1856273)!

08 March 2018 – Steve Martin and co-workers use our (4+3) methodology as a key step in their total synthesis of exotine A. [link]

07 March 2019 – Our paper studying the biological mechanism of the nuphar alkaloids has been published! [link]

05 November 2018 – Collaborative crowd-sourcing effort to screen natural products for important biological activity has been published. Congrats to Jason Rohde, Matt Hall and everyone else involved! [link]

18 October 2018 – Excited that Ji’s indole arylation paper [link] is one of Angewandte Chemie’s Top 20 Most Downloaded recent papers! #Top20Article [link]

30 July 2018 – Trauner and co-workers use our (4+3) methodology as a key step in their total synthesis of exotine B. [link] [Twitter]

30 January 2018 – Ji’s paper on the catalytic vinylogous cross-coupling reactions of rhenium vinylcrabenoids just published in Chem. Sci. [link]

10 January 2018 – Maria’s paper on the annulation of azaoxyallyl cations with nitriles and cyanamides just published in Org. Lett. [link]

05 October 2017 – Norris Cotton Cancer Center video featuring Jimmy Wu and other ACS cancer researchers at Dartmouth. See time stamps at 1m53s; 4m03s; and 5m41s.

12 July 2017 – Ji’s paper on small molecules with ant-MRSA activity was published in J. Antiobiotics (Tokyo) today! [link]

03 March 2017 − Ji’s paper on transition metal-free indole arylation reactions just published in Angew. Chem. Int. Ed. [link]

06 February 2017 − Hui and Tim’s paper on apoptotically active desmethyl/epimeric monomeric nuphar alkaloids has just appeared in JOC [link]

29 July 2016 − Martin, Maria, Hui, and Xinping’s paper on small molecule GLP-1 secretagogues was published in Scientific Reports [link]

05 February 2016 − Hui’s paper on the discovery of the 1st apoptotically-active monomeric nuphar alkaloids was published in Angew. Chem. Int. Ed. [link]

17 November 2015 − Maria’s paper on the synthesis of pyrroloindolines via dearoamative indole (3+2) reactions was just published in JACS. [link]

23 October 2015 − Hui’s paper on vinylogous Mukaiyama−Michael (vM−Michael) reactions was just published in Org. Lett. [link]

Nuphar Synthesis News Releases:
          25 August 2015: Norris Cotton Cancer Center [link]
          21 July 2015: EurekAlert! [link]

17 July 2015 − Sasha and Hui’s paper on the synthesis of the dimeric Nuphar alkaloids has just been published in Angew. Chem. Int. Ed. [link]

08 October 2014 Dartmouth NOW piece summarizes our research [link]

18 August 2014 − Markku’s paper on formal hydroamination reactions has been published. [link]

06 August 2014 − NIH grant was funded (NIGMS R01GM111638-01). [link]

30 July 2014 − Our review on catalytic nucleophilic fluorination reactions was just published. [link]

28 May 2014 − Our eROS submission on diethylphosphorothioic acids was just published. [link]

18 April 2014 − Hui’s paper on dearomative indole cyclization reactions just appeared in JACS on ASAP. [link]