Elliott awarded NCI K99 grant for Molecularly Guided Surgery

Jonathan Elliott, PhD, was awarded a “Pathway to Independence” grant from the National Cancer Institute in August 2016.  Entitled “Molecularly Guided Surgery for Improved Resection of Glioblastoma Multiforme,” the grant project aims to accelerate Professor Elliott’s promising research career by building upon Dartmouth’s ongoing work in fluorescence-guided surgery (FGS) with ABY-029, the agent approved by FDA for a first-in-human clinical trial.  These two-year grants are given to outstanding postdoctoral researchers to help them advance to tenure-track or equivalent faculty positions.  Funds support Dr. Elliott’s mentored-training program with a core group of NIH-funded researchers at Dartmouth Hitchcock Medical Center (DHMC), including Dr. David Roberts, with Professors Keith Paulsen and Brian Pogue at the Thayer School of Engineering, and Dr. Jack Hoopes in the Geisel School of Medicine. Professor Elliott will conduct a pre-clinical research project to develop and evaluate a new approach to molecular-guided surgery – intraoperative receptor concentration imaging (iRCI). 


Dartmouth Wins FDA Approval for New Fluorescent Agent to Guide Cancer Surgery

In a major milestone for Dartmouth and for the future of molecular guided cancer surgery, Dartmouth has gained FDA approval for a study that may give surgeons a new “guiding light” during cancer surgeries.  The approval gives Dartmouth the go-ahead for the first study involving humans of a fluorescent agent for guiding tumor surgery.  The agent, called ABY-029, binds to cancer cell receptors and highlights tumors during surgery.   Production of ABY-029 was coordinated by Dartmouth’s Thayer School of Engineering and Geisel School of Medicine, with Academic-Industrial partners Affibody AB, LI-COR Biosciences, and the University of Alabama at Birmingham using NCI grant funding.

thayer-paulsen-pritzker-8101“Our approach will dramatically accelerate the paradigm shift towards molecular guided surgical oncology,” says Keith Paulsen, the Robert A. Pritzker Professor of Biomedical Engineering and scientific director of Dartmouth’s Center for Surgical Innovation.

Read the full story at http://news.dartmouth.edu/news/2016/10/dartmouth-wins-fda-approval-aid-guide-cancer-surgery

Pogue selected as AIMBE Fellow

Brian Pogue, Professor of Engineering and Director of MS and PhD Programs, has been selected by the American Institute for Medical and Biological Engineering (AIMBE) as a new member of its College of Fellows.  AIMBE Fellows represent the top two percent of national medical and biological engineers, and are recognized for their scholarly work in the field.  Brian, who joins Thayer Professor John Zhang and Professor Emeritus Bob Dean as an AIMBE Fellow, was recognized for his work in biomedical optics and imaging.  Congratulations Brian!

Andreozzi wins AAPM Award

Dartmouth’s Jacqueline Andreozzi was awarded the 1st place prize in the 2015 John R. Cameron Young Investigators’ Competition by the American Association of Physicists in Medicine (AAPM).

The John R. Cameron Young Investigators Symposium features an annual competition for new investigators in honor of University of Wisconsin Professor Emeritus Dr. John Cameron, a founding member of the AAPM.  Of the many submissions from young investigators, reviewers selected the 10 highest scoring abstracts for presentation during a special symposium.  The top three award winners were recognized during the AAPM Annual Meeting Awards and Honors Ceremony on Monday, July 13, 2015, in Anaheim CA, each receiving a plaque and a cash award.

Jacqueline’s abstract is entitled “Rapid Treatment Field Uniformity Optimization for Total Skin Electron Beam Therapy Using Cherenkov Imaging” and it can be found at: Jacqueline Andreozzi AAPM abstract

Congratulations Jacqueline!



OiM Overlay GUI released

The Optics in Medicine Overlay GUI is a MATLAB-based graphical user interface which facilitates overlaying parametric maps on top of white-light images for:

  • Displaying fluorescence-whitelight fused images for surgical guidance
  • Exploring perceptual colormaps and plotting them on the 1931 CIE chromaticity diagram.
  • Testing color blindness compatibility
  • Determining best practices for colormap and transparency visualization

Questions, comments and bug reports can be made to Jonathan.T.Elliott@dartmouth.edu

(NEW) Download Overlay GUI v4.4.1-beta