The May 1, 2017 issue of the publication Clinical Cancer Research features fluorescence images of ex vivo brain tissue sections acquired by Assistant Professor Jonathan T. Elliott, PhD, of the Thayer School of Engineering.
The cover art (at left) shows images of tissue distribution of novel agent ABY-029 in green, 5-ALA-induced PpIX images in blue, and IRDye 680RD-CX in red. The distribution of these imaging agents in large F98 EGFR-positive tumors represent markers of EGFR expression, protoporphyrin metabolism and perfusion, respectively, which enable optically guided tumor identification.
