Thomas Jack, Ph.D.
Chair, Department of Biological Sciences
Dartmouth College
78 College Street
Life Sciences Center, 331
Hanover, NH 03755
thomas.p.jack@dartmouth.edu
Research Interests
The long-term goal of the lab is to understand the molecular mechanisms that underlie the development of plants. We study is the model plant Arabidopsis thaliana, in particular, the development of the Arabidopsis flower, which like most angiosperm flowers, consists of four organ types: sepals, petals, stamens, and carpels. We are interested in understanding the specification of organ identity and organ growth in flowers. Of particular interest is two genes: DORNRÖSCHEN-LIKE (DRNL), which encodes an AP2 domain transcription factor, and SUPERMAN (SUP). which encodes a putative transcriptional repressor.
Selected Research Publications
Xu, Y., Prunet, N., Gan, E.-S., Wang, Y., Stewart, D., Wellmer, F., Huang, J., Yamaguchi, N., Tatsumi, Y., Kojima, M., Kiba, T., Sakakibara, H., Jack, T. P., Meyerowitz, E. M., Ito, T. (2018). SUPERMAN regulates floral whorl boundaries through control of auxin biosynthesis. EMBO J. 37: e97499. doi: 10.15252/embj.201797499.
Prunet, N., Yang, W., Das, P., Meyerowitz ,E.M., Jack, T.P. (2017). SUPERMAN prevents class B gene expression and promotes stem cell termination in the fourth whorl of Arabidopsis thaliana flowers. PNAS. 2017 114:7166-7171. doi: 10.1073/pnas.1705977114.
Prunet, N., Jack, T. P., and Meyerowitz, E. M. (2016). Live confocal imaging of Arabidopsis flower buds. Dev Biol. 419, 114-120,
Prunet, N., Morel, P., Champelovier, P., Thierry, A.-M., Negrutiu, I., Jack, T., and Trehin, C. (2015). SQUINT promotes stem cell homeostasis and floral meristem termination in Arabidopsis through APETALA2 and CLAVATA signaling. J. Ex. Bot. 66, 6905-6916.
Wellmer, F., Bowman, J. L., Davies, B., Ferrandiz, C., Fletcher J. C., Franks, R. G., Graciet, E., Gregis, V., Ito, T., Jack, T. P., Jiao, Y., Kater, M. M., Ma, H., Meyerowitz, E. M., Prunet, N., and Riechmann, J. L. (2014). Flower Development: Open Questions and Future Directions. In Methods in Molecular Biology – Flower Development: Methods and Protocols (F. Wellmer and J.-L. Riechmann editors), 103-124.
Prunet, N. and Jack, T. (2014). Flower development in Arabidopsis – there’s more to it than learning your ABCs. In Methods in Molecular Biology – Flower Development: Methods and Protocols (F. Wellmer and J.-L. Riechmann editors), 3-33.
Biology Education Publications
Brancaccio-Taras, L., Pape-Lindstrom, P. A., Peteroy-Kelly, M., Aguirre, K. M., Awong-Taylor, J., Balser, T. C., Cahill, M., Frey, G., Jack, T., Kelrick, M., Marley, K. E., Miller, K. G., Osgood, M. P., Romano, S. L. Uzman, J. A., Zhao. J. (2016). The PULSE Vision & Change Rubrics: A valid and equitable tool to measure life sciences department transformation at all institution types. CBE Life Sci Educ. 2016 Winter; 15(4): ar60. doi: 10.1187/cbe.15-12-0260 PMCID: PMC5132357 PMID: 27856548.
Pape-Lindstrom, P. A., Jack, T., Miller, K. G., Aguirre, K. M., Awong-Taylor, J., Balser, T. C., Awong-Taylor, J., Brancaccio-Taras, L., Marley, K. E., Osgood, M. P., Peteroy-Kelly, M., Romano, S. L. (2015). PULSE pilot certification results. J. Microbiol. Ed. 16, 127-129.
Aguirre, K. M., Balser, T. C., Jack, T., Marley, K. E., Miller, K. G., Osgood, M. P., Pape-Lindstrom, P. A., and Romano, S. L. (2013). PULSE Vision & Change Rubrics. CBE-Life Sciences Ed. 12, 579-581.