Selected Literature

The publications below provide more in-depth arsenic research and information. In addition to the overview literature, click on the headings below to jump to that section, or simply scroll down the list.

Health EffectsPregnancy, Infants & ChildrenWaterFoodSmoking

Overviews on Arsenic Research and Information

Rogers SH, Rardin LR, Lawlor K, Chen CY, Borsuk ME. 2019. Communicating Arsenic’s Risks. International Journal of Environmental Research and Public Health. Int J Environ Res Public Health. 2019 Sep 16;16(18). pii: E3436. doi: 10.3390/ijerph16183436.

Cullen WR and Reimer KJ. 2017. Arsenic is Everywhere: Cause for Concern? Royal Society of Chemistry. 293 pps.

Carlin DJ, et al. 2016. Arsenic and Environmental Health: State of the Science and Future Research Opportunities. Environmental Health Perspectives. 124(7): 890–899.

Hughes MF, Beck BD, Chen Y, Lewis AS, Thomas DJ. 2011. Arsenic Exposure and Toxicology: A Historical Perspective. Toxicological Sciences. 123, 305-332.

Health Effects

Kevin S Hsu, Britton C Goodale, Kenneth H Ely, Thomas H Hampton, Bruce A Stanton, Richard I Enelow. 2020. Single cell RNA-seq analysis reveals that prenatal arsenic exposure results in long-term, adverse effects on immune gene expression in response to Influenza A infection. Toxicological Sciences. Toxicol Sci 2020 Jun 8;kfaa080. doi: 10.1093/toxsci/kfaa080.

Signes-Pastor AJ, Scot Zens M, Seigne J, Schned A, Karagas MR. 2019. Rice Consumption and Incidence of Bladder Cancer in the United States Population. Epidemiology. 2019 Mar;30(2):e4-e5. doi: 10.1097/EDE.0000000000000955.

Moon KA, Oberoi S, Barchowsky A, et al. 2018. A dose-response meta-analysis of chronic arsenic exposure and incident cardiovascular disease. Int J Epidemiol. 2018;47(3):1013. doi:10.1093/ije/dyy073

Goodale BC, Rayack EJ, Stanton BA. 2017. Arsenic Alters Transcriptional Responses to Pseudomonas Aeruginosa Infection and Decreases Antimicrobial Defense of Human Airway Epithelial Cells. Toxicology and Applied Pharmacology. Toxicol Appl Pharmacol. 2017 Sep 15;331:154-163. doi: 10.1016/j.taap.2017.06.010.

Baris D … Silverman DT, et al. 2016. Elevated Bladder Cancer in Northern New England: The Role of Drinking Water and Arsenic. Journal of the National Cancer Institute. 108 (9): djw099.

Karagas MR, Gossai A, Pierce B, Ahsan H. 2015. Drinking Water Arsenic Contamination, Skin Lesions, and Malignancies: A Systematic Review of the Global Evidence. Current Environmental Health Reports. 2015 Mar;2(1):52-68. doi: 10.1007/s40572-014-0040-x.

Gilbert-Diamond D, Li Z, Perry AE, Spencer SK, Gandolfi AJ, Karagas MR. 2013. A Population-Based Case-Control Study of Urinary Arsenic Species and Squamous Cell Carcinoma in New Hampshire, USA. Erratum in: Environmental Health Perspectives. 2013 Oct;121(10):1154-60. doi: 10.1289/ehp.1206178.

Naujokas MF, et al. 2013. The Broad Scope of Health Effects from Chronic Arsenic Exposure: Update on a Worldwide Public Health Problem. Environmental Health Perspectives. 2013. 121(3): p. 295.

Pregnancy, Infants and Children

Adachi-Mejia A, Murray CJ, Karagas M. 2019. “If Providers Had Recommended It, We Would Have Had It Tested”: Rural Mother’s Perspectives on Barriers and Facilitators to Testing for Arsenic in Their Well Water. J Environ Health. 2019;82(3): 26-32.

He X, Karagas MR, Murray C. 2018. Impact of receipt of private well arsenic test results on maternal use of contaminated drinking water in a U.S. population. Sci Total Environ. 2018;643:1005–1012. doi:10.1016/j.scitotenv.2018.06.228

Farzan SF, Gossai A, Chen Y, Chasan-Taber L, Baker E, Karagas M. 2016. Maternal Arsenic Exposure and Gestational Diabetes and Glucose Intolerance in the New Hampshire Birth Cohort Study. Environmental Health. 2016 Nov 8;15(1):106. DOI: 10.1186/s12940-016-0194-0.

Farzan SF, Li Z, Korrick SA, et al. 2016. Infant Infections and Respiratory Symptoms in Relation to In Utero Arsenic Exposure in a US Cohort. Environmental Health Perspectives. doi: 10.1289/ehp.1409282.

Gilbert-Diamond D, Emond JA, Baker ER, Korrick SA, Karagas MR. 2016. Relation between in Utero Arsenic Exposure and Birth Outcomes in a Cohort of Mothers and Their Newborns from New Hampshire. Environmental Health Perspectives. 2016 Aug;124(8):1299-307. doi: 10.1289/ehp.1510065.

Carignan CC, Cottingham KL, Jackson BP, Farzan SF, Gandolfi AJ, Punshon T, Folt CL, Karagas MR. 2015. Estimated Exposure to Arsenic in Breastfed and Formula-Fed Infants in a United States Cohort. Environmental Health Perspectives. v. 123, no. 5, p. 500-506.

Farzan SF, Chen Y, Wu F, Jiang J, Liu M, Baker E, Korrick SA, Karagas MR. 2015. Blood Pressure Changes in Relation to Arsenic Exposure in a U.S. Pregnancy Cohort. Environmental Health Perspectives. Environ Health Perspect. 2015 Oct;123(10):999-1006. doi: 10.1289/ehp.1408472.

Farzan SF, Karagas MR, Chen Y. 2013. In Utero and Early Life Arsenic Exposure in Relation to Long-Term Health and Disease. Toxicology and Applied Pharmacology. 2013;272(2):384–390.

Farzan SF, Korrick S, Li Z, et al. 2013. In Utero Arsenic Exposure and Infant Infection in a United States Cohort: A Prospective Study. Environmental Research. 2013;126:24–30.


Yang, Q., Flanagan, S. V., Chillrud, S., Ross, J., Zeng, W., Culbertson, C., . . . Zheng, Y. 2020. Reduction in drinking water arsenic exposure and health risk through arsenic treatment among private well households in Maine and New Jersey, USA. Science of the Total Environment, 738, 139683. doi:

Flanagan, S. V., J. A. Gleason, S. E. Spayd, N. A. Procopio, M. Rockafellow-Baldoni, S. Braman, S. N. Chillrud, and Y. Zheng. 2018. Health protective behavior following required arsenic testing under the New Jersey Private Well Testing Act. International Journal of Hygiene and Environmental Health 221:929-940. 

Barnaby R, Liefeld A, Jackson BP, Hampton TH, Stanton BA. 2017. Effectiveness of Table Top Water Pitcher Filters to Remove Arsenic from Drinking Water. Environmental Research. Environ Res. 2017 Oct;158:610-615. doi: 10.1016/j.envres.2017.07.018.

Zheng, Y., & Flanagan, S. V. 2017. The case for universal screening of private well water quality in the US and testing requirements to achieve it: evidence from arsenic. Environmental Health Perspectives, 125(8), 085002.

Smith AE, Lincoln RA, Paulu C, Simones TL, Caldwell K, Jones RL, Backer LC. 2016. Assessing Arsenic Exposure in Households Using Bottled Water or Point-of-use Treatment Systems to Mitigate Well Water Contamination. Science of the Total Environment. v. 544, p. 701-710.

Ayotte JD, Belaval M, Olson SA, Burow KR, Flanagan SM, Hinkle SR, Lindsey BD. 2015. Factors Affecting Temporal Variability of Arsenic in Groundwater Used for Drinking Water Supply in the United States. Science of the Total Environment. v. 505, p. 1370-1379.

Zheng Y, and Ayotte JD. 2015. At the Crossroads: Hazard Assessment and Reduction of Health Risks from Arsenic in Private Well Waters of the Northeastern United States and Atlantic Canada. Science of The Total Environment. Volume 505, 1 February 2015, Pages 1237–1247.

Nuckols JR, Freeman LE, Lubin JH, et al. 2011. Estimating water supply arsenic levels in the New England Bladder Cancer Study [published correction appears in Environ Health Perspect. 2011 Dec;119(12):A509]. Environ Health Perspect. 2011;119(9):1279-1285. doi:10.1289/ehp.1002345

Severtson, D. J., Baumann, L. C., & Brown, R. L. 2006. Applying a health behavior theory to explore the influence of information and experience on arsenic risk representations, policy beliefs, and protective behavior. Risk Analysis: An International Journal, 26(2), 353-368.  


Karagas MR, Punshon T, Davis M, Bulka CM, Slaughter F, Karalis D, Argos M, Ahsan H. 2019. Rice Intake and Emerging Concerns on Arsenic in Rice: a Review of the Human Evidence and Methodologic Challenges. Current Environmental Health Reports. Curr Environ Health Rep. 2019 Nov 23. doi: 10.1007/s40572-019-00249-1.

Manjon, I, Ramirez-Andreotta, MD. 2019. A Dietary Assessment Tool to Estimate Arsenic and Cadmium Exposures from Locally Grown Foods. Environmental Geochemistry and Health. doi: 10.1007/s10653-019-00486-1.

Manjon I, Ramirez-Andreotta, MD, Saez AE, Root RA, Hild J, Janes K, Alexander-Ozinskas A. 2019. Ingestion and Inhalation of Metal(loid)s Through Preschool Gardening: An Exposure and Risk Assessment in Legacy Mining Communities. Science of the Total Environment. doi: 10.1016/j.scitotenv.2019.134639.

Nachman KE, Punshon T, Rardin AJ, Murray CJ, … Karagas MR. 2018. Opportunities and Challenges for Dietary Arsenic Intervention. Environ Health Perspect. 126(8):84503. doi:10.1289/EHP399.

Cubadda F, et al. 2017. Human Exposure to Dietary Inorganic Arsenic and Other Arsenic Species: State of Knowledge, Gaps and Uncertainties. Science of the Total Environment. v. 579, 1 February 2017, Pages 1228–1239.

Davis MA, Signes-Pastor AJ, Argos M, Slaughter F, Pendergrast C, Punshon T, Gossai A, Ahsan H, Karagas MR. 2017. Assessment of Human Dietary Exposure to Arsenic Through Rice. Science of the Total Environment. Sci Total Environ. 2017 May 15;586:1237-1244. doi: 10.1016/j.scitotenv.2017.02.119.

Nachman KE, et al. 2017. Mitigating Dietary Arsenic Exposure: Current Status in the United States and Recommendations for an Improved Path Forward. Science of the Total Environment. 2017 Mar 1;581-582:221-236. doi: 10.1016/j.scitotenv.2016.12.112. Epub 2017 Jan 5.

Punshon T, et al. 2017. Understanding Arsenic Dynamics in Agronomic Systems to Predict and Prevent Uptake by Crop Plants. Science of the Total Environment. Volumes 581–582, 1 March 2017, Pages 209–220.

Taylor V, et al. 2017. Human Exposure to Organic Arsenic Species from Seafood. Science of the Total Environment. Volume 580, 15 February 2017, Pages 266–282.

Karagas, M, et al. 2016. Association of Rice and Rice-Product Consumption with Arsenic Exposure Early in Life. JAMA Pediatrics. JAMA Pediatr. Jun 1; 170(6): 609–616. doi: 10.1001/jamapediatrics.2016.0120.

Molin M, Ulven SM, Meltzer HM, Alexander J. 2015. Arsenic in the Human Food Chain, Biotransformation and Toxicology – Review Focusing on Seafood Arsenic. Journal of Trace Elements in Medicine and Biology. 31: 249-259.

Kurzius-Spencer M, Burgess JL, Harris RB, Hartz V, Roberge J, Huang S, et al., 2014. Contribution of Diet to Aggregate Arsenic Exposures—an Analysis Across Populations. Journal of Exposure Science and Environmental Epidemiology. 24, 156–162.

Gilbert-Diamond D, Cottingham KL, Gruber JF, et al. 2011. Rice Consumption Contributes to Arsenic Exposure in US Women. Proceedings of the National Academy of Sciences of the United States of America. 2011;108(51):20656–20660.


Farzan SF, Chen Y, Rees J.R, Zens MS, Karagas MR. 2015. Risk of Death from Cardiovascular Disease Associated with Low-level Arsenic Exposure Among Long-term Smokers in a US Population-Based Study. Toxicology and Applied Pharmacology. v. 287, no. 2, p. 93-97.

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