Publications

Using Fluorescence In Situ Hybridization (FISH) to Monitor the State of Arm Cohesion in Prometaphase and Metaphase I Drosophila Oocytes.
Perkins AT, Bickel SE.
J Vis Exp
. 2017 Dec 6;(130). doi: 10.3791/56802.
PMID:29286418
Link to Video

Oxidative stress in oocytes during mid-prophase induces premature loss of cohesion and chromosome segregation errors.
Perkins, A.T., Das, T.M., Panzera, L.C. and Bickel, S.E.
PNAS 2016 Oct 17. pii: 201612047. [Epub ahead of print]
PMID:27791141

Heterochromatin-Associated Proteins HP1a and Piwi Collaborate to Maintain the Association of Achiasmate Homologs in Drosophila Oocytes.
Giauque CC, Bickel SE.
Genetics. 2016; 203(1):173-89.
PMID: 26984058
PMCID: PMC4858772

Rejuvenation of meiotic cohesion in oocytes during prophase I is required for chiasma maintenance and accurate chromosome segregation.
Weng KA, Jeffreys CA, Bickel SE.
PLoS Genetics. 2014; 10(9):e1004607.
PMID: 25211017
PMCID: PMC4161318

Heterochromatin-mediated association of achiasmate homologs declines with age when cohesion is compromised.
Subramanian VV, Bickel SE.
Genetics. 2009; 181(4):1207-18.
PMID: 19204374
PMCID: PMC2666492

Aging predisposes oocytes to meiotic nondisjunction when the cohesin subunit SMC1 is reduced.
Subramanian VV, Bickel SE.
PLoS Genetics. 2008; 4(11):e1000263.
PMID: 19008956
PMCID: PMC2577922

Corona is required for higher-order assembly of transverse filaments into full-length synaptonemal complex in Drosophila oocytes.
Page SL, Khetani RS, Lake CM, Nielsen RJ, Jeffress JK, Warren WD, Bickel SE, Hawley RS.
PLoS Genetics. 2008; 4(9):e1000194.
PMID: 18802461
PMCID: PMC2529403

Functional links between Drosophila Nipped-B and cohesin in somatic and meiotic cells.
Gause M, Webber HA, Misulovin Z, Haller G, Rollins RA, Eissenberg JC, Bickel SE, Dorsett D.
Chromosoma. 2008; 117(1):51-66. NIHMSID: NIHMS40393
PMID: 17909832
PMCID: PMC2258212

Regulation of meiotic cohesion and chromosome core morphogenesis during pachytene in Drosophila oocytes.
Khetani RS, Bickel SE.
Journal of Cell Science. 2007; 120(Pt 17):3123-37.
PMID: 17698920

Aging (not so) gracefully.
Bickel SE.
Nature Genetics. 2005; 37(12):1303-4.
PMID: 16314861

The cohesion protein ORD is required for homologue bias during meiotic recombination.
Webber HA, Howard L, Bickel SE.
The Journal of Cell Biology. 2004; 164(6):819-29.
PMID: 15007062
PMCID: PMC2172286

A proposed role for the Polycomb group protein dRING in meiotic sister-chromatid cohesion.
Balicky EM, Young L, Orr-Weaver TL, Bickel SE.
Chromosoma. 2004; 112(5):231-9.
PMID: 14669021

A model system for increased meiotic nondisjunction in older oocytes.
Jeffreys CA, Burrage PS, Bickel SE.
Current Biology : CB. 2003; 13(6):498-503.
PMID: 12646133

Meiotic cohesion requires accumulation of ORD on chromosomes before condensation.
Balicky EM, Endres MW, Lai C, Bickel SE.
Molecular Biology of the Cell. 2002; 13(11):3890-900.
PMID: 12429833
PMCID: PMC133601

The sister-chromatid cohesion protein ORD is required for chiasma maintenance in Drosophila oocytes.
Bickel SE, Orr-Weaver TL, Balicky EM.
Current Biology : CB. 2002; 12(11):925-9.
PMID: 12062057

Maintenance of sister-chromatid cohesion at the centromere by the Drosophila MEI-S332 protein.
Tang TT, Bickel SE, Young LM, Orr-Weaver TL.
Genes & Development. 1998; 12(24):3843-56.
PMID: 9869638
PMCID: PMC317262

Genetic interactions between mei-S332 and ord in the control of sister-chromatid cohesion.
Bickel SE, Moore DP, Lai C, Orr-Weaver TL.
Genetics. 1998; 150(4):1467-76.
PMID: 9832524
PMCID: PMC1460439

Mutational analysis of the Drosophila sister-chromatid cohesion protein ORD and its role in the maintenance of centromeric cohesion.
Bickel SE, Wyman DW, Orr-Weaver TL.
Genetics. 1997; 146(4):1319-31.
PMID: 9258677
PMCID: PMC1208078

Holding chromatids together to ensure they go their separate ways.
Bickel SE, Orr-Weaver TL.
BioEssays : 1996; 18(4):293-300.
PMID: 8967897

Identification of ORD, a Drosophila protein essential for sister chromatid cohesion.
Bickel SE, Wyman DW, Miyazaki WY, Moore DP, Orr-Weaver TL.
The EMBO Journal. 1996; 15(6):1451-9.
PMID: 8635478
PMCID: PMC450050