IMPROVE AKI: A Cluster-Randomized Trial of Team-Based Coaching Interventions to IMPROVE Acute Kidney Injury
Over 2 million people in the United States undergo diagnostic or interventional cardiac catheterization each year. Acute kidney injury (AKI), a patient safety metric set by the National Quality Forum, occurs in up to 14% of all patients following a procedure and up to 50% in patients with pre-existing chronic kidney disease (CKD), making AKI the most prevalent adverse event. Patients developing AKI have an increased risk of serious adverse events. There are widely accepted interventions to prevent AKI in patients undergoing cardiac catheterization. IMPROVE AKI aims to test the implementation of these evidence-based preventive interventions through a Virtual Learning Collaborative (VLC) with and without the novel use Automated Surveillance Reporting (ASR) intervention to change clinical practice and improve patient safety in common diagnostic procedures. Our research team has demonstrated AKI can be prevented in 28% of patients with CKD through a large regional pilot. Our objective is to conduct a national randomized clinical trial testing the use of VLC or TA with or without a plug-in ASR toolkit to determine if ASR significantly improves outcomes for patients undergoing procedures with contrast dye to overcome the inconsistent application of known ways to prevent AKI.
Study status: In Analysis
To learn more about this project, please see major publications below:
- Team-based coaching intervention to improve contrast-associated acute kidney: A cluster-randomized trial
- Modifying the risk of contrast-associated acute kidney injury in percutaneous coronary interventions and transcatheter aortic valve implantations
- Death, coronary revascularization choices, and chronic kidney disease
- Maintaining a national acute kidney injury risk prediction model to support local quality benchmarking