AMI

Information Extraction from EMRs to Predict Readmission Following Acute Myocardial Infarctions 

Each year, nearly 635,000 people in the United States will have their first acute myocardial infarction (heart attack) and about 20% will be re-hospitalized within 30-days of their incident discharge. Re-hospitalizations are costly for health systems, insurers, patients and their families. As such, there is great value and emphasis placed on readmission reduction programs, many of which are centered around a predictive tool. The Brown Lab developed a clinical decision support tool to enumerate the risk for 30-day hospital readmissions among patients hospitalized with an AMI. The project harmonized electronic health record data from Dartmouth Hitchcock Health and Vanderbilt University Medical Center to the Observational Medical Outcomes Partnership (OMOP) common data model. In addition, a natural language processing (NLP) model called Moonstone was deployed on clinical notes from both health systems, which extracted information on social risk factors. Together, the structured clinical data and NLP-derived social risk factors were used in the development and external validation of five prediction models. Best performing models achieved good discriminatory and calibration performance.  

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Study status: Final analysis

To learn more about this project, please see major publications below: