High-throughput genomic, proteomic, metabolomic, and immune-profiling technologies provide a wealth of data to interrogate basic biological processes, changes in cellular/organismal populations, and the molecular basis of disease at levels ranging from the whole organism to single cells. The rapid advancement of high-throughput technologies for assessing biological systems has generated a significant demand at Dartmouth for platforms that support ‘-omics’ in single cells, as well as interdisciplinary approaches to computational biology.
The goal of this COBRE program is to establish a Center for Quantitative Biology (CQB), to support and enhance NIH-funded quantitative biological research at Dartmouth and to facilitate its integration with experimental biology. The CQB will draw upon faculty in the Arts & Sciences, Thayer School of Engineering, and the Geisel School of Medicine at Dartmouth. The Center will recruit and provide a cohesive community for diverse scientists with homes in departments spanning Geisel, Arts & Sciences and the Thayer School, including Biomedical Data Science, Molecular & Systems Biology, Biochemistry & Cell Biology, Epidemiology, Microbiology & Immunology, Biological Sciences, Computer Science and Mathematics. Through its emphasis on next-generation data, the CQB will bring together and enhance initiatives in computational biology, bioinformatics, and experimental genomics across Dartmouth.