Gastrointestinal Biology Core (P30)

Co-Directors:  Bruce Stanton, PhD, Andrew C. Vail Professor of Microbiology and Immunology and George O’Toole, PhD, Professor of Microbiology and Immunology

Description: The mission of the Gastrointestinal Biology Core (GIBC) is to advance basic science, as well as translational and discovery studies relevant to interactions of microbes with host epithelial cells from the intestine, provide expertise using a co-culture platform of bacterial biofilms on human epithelial cells, and provide a range of intestinal cell lines, including primary human epithelial cells, organoids and 2D cultures from cystic fibrosis (CF) and non-CF donors, to support studies assessing host-microbe interactions relevant to the gut, endocrine, and systemic CF disease, including CFRD.  The Core also assists in the development of new cell lines and other methodologies to advance the science of Center members and Pilot Project awardees.

Location: The GIBC is located in the Remsen Building on the Hanover campus of the Geisel School of Medicine.

Staff: Roxanna Barnaby, Ruina Bao, Amanda Nymon

Contact: George O’Toole (georgeo@dartmouth.edu) or Bruce Stanton (bas@dartmouth.edu)