David Leib

David Leib PhD is Professor and Chair of Microbiology and Immunology at The Geisel School of Medicine.  He obtained his BSc from the University of Birmingham and his PhD from the University of Liverpool both in the UK, with postdoctoral training at Harvard Medical School. He has worked in the field of herpesvirus pathogenesis, immunology, and molecular biology for almost 40 years developing novel imaging methods and host and viral genetic frameworks for studying the virulence and immune evasion properties of herpes simplex virus. His work has led to preclinical testing of a variety of replication-deficient vaccine candidates in collaboration with David Knipe at Harvard. More recently, in collaboration with Margaret Ackerman, his lab has assessed the abilities of engineered monoclonal antibodies to alter the outcome of neonatal HSV infections. This recent work has also focused on developing new models to study the neurodevelopmental and behavioral sequelae that often accompany infection of the developing brain. His lab has shown that maternal immunization is a powerful route by which to attain protection of the neonatal nervous system. His teaching to undergraduate and graduate students at Dartmouth focuses on the pathogenesis of viruses, and how viral epidemics, pandemics, and vaccines have shaped human history.