Production, Crystallization, and Structure Determination of the IKK-binding Domain of NEMO
Tag archive for: NEMO
NIGMS R01 Award
Posted in grants
Project Title: Targeting the IKK-Binding Domain of NEMO for Inhibitors Discovery Notice of Award: 08/30/2019 Project Period: 09/01/2019 – 07/31/2023 $ 1,476,000
The IKK-binding domain of NEMO is an irregular coiled coil with a dynamic binding interface
Posted in publication
Adam H. Barczewski, Michael J. Ragusa, Dale F. Mierke & Maria Pellegrini Scientific Reports volume 9, Article number: 2950 (2019) Abstract NEMO is an essential component in the activation of the canonical NF-κB…
Read MoreThe IKK-binding domain of NEMO is an irregular coiled coil with a dynamic binding interface
NIAMS R03 award
Posted in grants
“Targeting the IKK-binding Domain of NEMO for Inhibitors Discovery” Issue Date: 09/12/2014 Project Period: 09/20/2014 – 08/31/2017