A $3 million grant was recently awarded by the Department of Defense’s (DOD) Combat Casualty Care Research Program to a team of researchers from the Thayer School of Engineering, the Geisel School of Medicine, and Dartmouth-Hitchcock Medical Center (DHMC) Emergency Department. Professor Jonathan Elliott is member of this team of doctors and researchers working on developing a non-invasive system that can help doctors in hospitals as well as military setting detect internal hemorrhaging in trauma patients that are otherwise stable.
Dr. Elliott’s role is to develop a new light sensor that will allow the device to detect internal injuries by determining the amount of oxygen in the patient’s blood. The device will also use spectrometers to detect physiological changes in the patient’s body that are related to shock.
This ground-breaking project was inspired by information from military doctors who treat battlefield patients who initially appear to be stable but then deteriorate due to internal bleeding that cannot be readily detected.
At the Photonics Ireland 2018 conference, Thayer School of Engineering PhD student Samuel Streeter was the runner-up prize winner in the SPIE-sponsored poster contest. His poster was entitled “Exploring texture analysis methods for high spatial frequency structured light imagery of tumour tissue.”
Dr. Andrew Brown, Senior Director of Global Business Development at SPIE, awarded the prizes based on their scientific content, visual presentation and presentation by the students during the poster session. This year’s winners came from a very competitive field. Congratulations Sam!
Physics World recently published a story about Thayer School of Engineering graduate Jacqueline Andreozzi, PhD, and her presentation at the 2018 AAPM Annual Meeting on the use of Cherenkov imaging for beam measurements in a MR-linear accelerator.
Jacqueline and the Dartmouth research team used a MR-linac to irradiate a water tank and measured Cherenkov emissions with an intensified CMOS sensor. Using a remote triggering device, they synchronized the acquired images to the radiation pulses from the MR-linac. Because the CMOS sensor can more easily collect red/near-infrared photons, the Dartmouth team demonstrated through these simulations that the number of detected Cherenkov photons is proportional to radiation dose.
Dr. Andreozzi concluded that Cherenkov imaging is a MR-compatible method for measuring MR-linac doses that is both rapid and repeatable. Importantly, Cherenkov imaging also has the potential for expansion to small beam dosimetry.
Jacqueline is now a Medical Physics Resident in the Department of Radiation Oncology at the University of Florida.
Congratulations to Optics in Medicine faculty member and Assistant Professor at Geisel School of Medicine Kimberley Samkoe, PhD on receiving an R37 Method to Extend Research in Time (MERIT) Award from the National Cancer Institute (NCI). The R37 MERIT Award enables NCI-funded Early Stage Investigators to obtain an expedited 2-years of funding in addition to an already funded 5-year R01 award.
Dr. Samkoe’s R37 MERIT Award is entitled, “Paired-Agent Imaging for Resection during Surgery (PAIRS) for Head and Neck Cancers” and focuses on improving outcomes of patients with head and neck cancers by refining the surgeon’s ability to remove all residual cancer cells. The proposed paired-agent imaging technique uses plasma transport kinetics to separate the signals of a tumor-targeted molecular imaging agent and a non-targeted control agent, isolating true molecular-bound signal. If successful, this technology will ultimately allow clinicians to identify and remove residual cancer cells at the boundary where tumor meets normal tissue; thus, maximizing patient survival and reducing life-long surgery-induced complications.
At it’s Annual Meeting this summer, the Education Council of AAPM honored innovators in Medical Physics Education. Thayer School of Engineering PhD student Irwin Tendler was selected to present his abstract entitled “Scintillator Target Imaging Provides Accurate Remote Multi-Site Surface Dosimetry.”
Irwin was awarded 3rd prize for his presentation in which he presented clinical data from the application of time-gated imaging of small scintillator dots placed on the skin surface of patients receiving irradiation. Detection of these point dosimeters with a camera that measures Cherenkov emissions (C-Dose camera by DoseOptics LLC) allowed for quantitative skin dose estimation from the image analysis. The data were validated with OSLD dosimetry used at the same time. Dartmouth’s approach provides the first methodology for remote quantitative imaging dosimetry.
Irwin was also the 2nd place winner of the National Young Investigator Symposium at the AAPM Spring Clinical meeting.
July 24 – Qianqian Fang, PhD, Assistant Professor, Bioengineering, Northeastern University – “Computationally enhanced diffuse optical tomography”
August 7 – Mamadou Diop, PhD, Assistant Professor/Scientist, Western University, Canada – “Advanced optical systems and methods for noninvasive neuromonitoring and assessing joint inflammation”
August 14 – Xavier Intes, PhD, Professor, Co-Director BioImaging Center, BME department, Rensselaer Polytechnic Institute – “Optical Molecular Imaging Beyond the Microscopy Depth Limit”
August 21 – Darren Roblyer, PhD, Assistant Professor, Department of Biomedical Engineering, Boston University – “Diffuse Optics In Cancer: New Developments in Wearables, High Speed Tomography, and Short-Wave Infrared Imaging”