COURSES IN EXPERIMENTAL AND MOLECULAR MEDICINE
101. Graduate Core Course in Experimental and Molecular Medicine I
07F Offered every year
This course offers a general introduction to molecular medicine through principles from cell biology, molecular biology, neurobiology and physiology. Basic biological concepts will be integrated with clinical correlations and translational research. The class will meet 6 hours per week and combine both lectures and readings from the primary literature. Teaching modules will cover Integration of Biological Systems, Macromolecular Structure, Nuclear Processes, Protein Synthesis, turnover and trafficking, and Metabolism. Course director: DeLeo. Module leaders: Galton, Bartlett, Cole, Martin.
102. Graduate Core Course in Experimental and Molecular Medicine II
08W Offered every year
This course is a continuation of PEMM 101 and offers a general introduction to molecular medicine through principles from cell biology, molecular biology, neurobiology and physiology. Basic biological concepts will be integrated with clinical correlations and translational research. The class will meet 6 hours per week and combine both lectures and readings from the primary literature. Teaching modules will cover Plasma membrane receptors: channels and transporters, Plasma membrane receptors: adhesion, motility, proliferation and survival, Immunology and Inflammation. Course director: DeLeo. Module leaders: Hwa, DeLeo, Shworak.
103. Biostatistics
Offered in 2007-2008, term to be arranged
124. Ethical Conduct of Research (Identical to Physiology 124 and Pharmacology and Toxicology 124)
07F: Arrange. Offered every year
There will be approximately seven one-hour lecture/discussion sessions with the times to be arranged. Topics will include: scientific freedom, ethical treatment of data, ethical use of laboratory animals, priority of discovery, fraud and deception, and science and the political process.
Faculty lectures and discussion. Instructors: North, Lomax, Green, Brown, Hoopes, Kavanagh, and others.
126. Cancer Biology
09S: Arrange. Offered in alternate years
This course will present a comprehensive survey of the biology, biochemistry, pharmacology, and genetics of cancer. Students will become familiar with such areas as cancer terminology, epidemiology, carcinogenesis, tumor promotion, metastasis, oncogenes, tumor suppressor genes, tumor viruses, growth factors, hormones, immunology, and therapy. Where possible, emphasis will be placed on the most recent cell and molecular aspects of cancer. The class will be in lecture format and meet for 3 hours each week.
Faculty lectures and discussion. Prerequisite: Core course in PEMM or MCB, or permission of instructor. Instructors: Eastman (course director) and others.
129. Molecular Pharmacology
08S: Arrange. Offered every year
The principles of ligand reactions with the receptors and the resulting changes in cellular signaling will be discussed in lecture format. Topics will include the cellular and molecular basis for pharmacologic selectivity, for receptor theory and kinetics, for specific receptor actions. Emphasis will be placed on recent developments in receptor biology and signaling cascades and on the methodologies required to study these processes. The course will meet 4 hours per week and course materials will include current literature reviews and research articles.
Faculty lectures and discussion. Prerequisite: permission of the instructor. Instructors: Robbins (course director) and others.
131. Current Approaches in Experimental Therapeutics
09W: Arrange. Offered in alternate years
This course will present a survey of current methods and approaches in pharmacologic, molecular and experimental therapeutic research. Topics will include pharmacogenomics, pharmacokinetics, functional genomics, in vivo imaging, global gene expression, proteomics, gene targeting, gene therapy and drug screening and delivery. The class will be in lecture format with student discussion and participation. The class will meet for 3 hours each week.
Faculty lectures and discussion. Prerequisite: permission of instructor. Instructors: Spinella and DiRenzo (course directors) and others.
271. Advanced Biomedical Sciences
08S Offered every year
Physiology is the study of how the body’s major systems are organized and how they act and interact with one another to enable the individual to adapt and survive in the face of changing needs and resources. The purpose of the Advanced Biomedical Sciences course is to help graduate students to gain a sophisticated understanding of the evolution and control of physiological systems. The focus of the course is on the physical, chemical and molecular mechanisms that achieve and regulate such processes as energy production, reproduction, growth, motility, secretion and the uptake, transport, metabolism and excretion of biologically important materials.
Instructor: Bartlett.
275. Vascular Biology
08S Offered every year
The principles of development, organization and function of the cardiovascular tree in health and disease will be discussed in lecture format. Topics will include the physiology and regulation of vasculature as an organ system, the molecular and cellular biology of endothelial cell function, and the molecular basis of the disorders of the vascular system. Emphasis will be placed on molecular aspects of cardiovascular disease such as atherosclerosis, diabetes, inflammation and neovascularization. The course will meet 4 hours per week. Course materials will include current literature reviews and research articles.
Instructor: Stan.
137. Project Research (Qualifying Examination)
All terms: Arrange
141. Research Rotation 1
All terms: Arrange
142. Research Rotation 2
All terms: Arrange
143. Research Rotation 3
All terms: Arrange
297. Level I: part-time research: 1 course equivalent
All terms: Arrange
298. Level II: part-time research: 2 course equivalent
All terms: Arrange
299. Level III: full-time thesis research: 3 course equivalent
All terms: Arrange