Ultrahigh Dose Rate Radiotherapy (FLASH-RT)
Radiotherapy with ultra high dose rates, termed FLASH-RT, have demonstrated superior normal tissue sparing than conventional radiotherapy while retaining comparable tumor control. With FLASH-RT, 1) toxicities can be further reduced to improve patient life quality and 2) dose can be escalated to fight against radio-resistance cancer that would be otherwise insufficiently treated.
At Dartmouth, we conduct researches in FLASH-RT that span a range of hardware and software development, chemical and molecular sensing, pre-clinical studies with small and large animals and veterinary treatments, with the ultimate goals being uncovering the FLASH mechanisms as well as realizing its clinical translations.