Publications

Featured Publications:

Excess histone H3 is a Chk1 inhibitor that controls embryonic cell cycle progression in the early Drosophila embryo
Y Shindo & AA Amodeo, Current Biology, 2021.

The nuclear to cytoplasmic ratio directly regulates zygotic transcription in Drosophila through multiple modalities
S  Syed*, H Wilky*, J Raimundo, B Lim♦, & AA Amodeo♦,PNAS, 2021.

Dynamics of Free and Chromatin-Bound Histone H3 during Early Embryogenesis
Y Shindo & AA Amodeo, Current Biology, 2019.

Histone titration by DNA sets the threshold for the mid-blastula transition in Xenopus
AA Amodeo, D Jukam, AF Straight & JM Skotheim  PNAS, 2015.

All Research Publications:

Local nuclear to cytoplasmic ratio regulates chaperone-dependent H3 variant incorporation during zygotic genome activation
AD Bhatt, MG Brown, AB Wackford, Y Shindo, AAmodeo, bioRxiv, 2024

Bellymount-Pulsed Tracking: A Novel Approach for Real-Time In vivo Imaging of Drosophila Abdominal Tissues
S Balachandra, AAmodeo, bioRxiv, 2024

Differential nuclear import sets the timing of protein access to the embryonic genome
T Nguyen, E Costa, T Deibert, J Reyes, F Keber, M Stadlmeier, M Gupta, C K Kumar, A A Amodeo, J C Gatlin, M Wühr, Nature Communications, 2022

Modeling the role for nuclear import dynamics in the early embryonic cell cycle
Y Shindo♦ & AA Amodeo♦, Biophysical Journal, 2021.

Excess histone H3 is a Chk1 inhibitor that controls embryonic cell cycle progression in the early Drosophila embryo
Y Shindo & AA Amodeo, Current Biology, 2021.

The nuclear to cytoplasmic ratio directly regulates zygotic transcription in Drosophila through multiple modalities
S  Syed*, H Wilky*, J Raimundo, B Lim♦, & AA Amodeo♦,PNAS, 2021. (Featured preLight)

Molecular genetics of maternally-controlled cell divisions
EW Abrams, R Fuentes, FL Marlow, M Kobayashi, H Zhang, S Lu, L Kapp, SR Joseph, A Kugath, T Gupta, V Lemon,  G Runke, AA Amodeo, NL Vastenhouw, MC Mullins, PLOS Genetics, 2020.

Histone concentration regulates the cell cycle and transcription in early development
S Chari*, H Wilky*, J Govindan & AA Amodeo, Development, 2019.

Dynamics of Free and Chromatin-Bound Histone H3 during Early Embryogenesis
Y Shindo & AA Amodeo, Current Biology, 2019.

Histone titration by DNA sets the threshold for the mid-blastula transition in Xenopus
AA Amodeo, D Jukam, AF Straight & JM Skotheim  PNAS, 2015.

Reviews and Meeting Reports:

The Nuclear-to-Cytoplasmic Ratio: Coupling DNA Content to Cell Size, Cell Cycle, and Biosynthetic Capacity
S Balachandra, S Sarkar & AA Amodeo Annual Reviews of Genetics, 2022.

Versatile roles for histones in early development
Y Shindo♦ , M Brown & AA Amodeo♦, Current Opinion in Cell Biology, 2022.

Early development: the journey from oocyte to embryo
(EMBO ZGA Meeting Report)
AA Amodeo*, JGassler*, K Kuznetsova*, & P Zegerman, The Node, 2020.

​Cell size. In: Size Control in Biology, from Organelles to Organisms
AA Amodeo & JM Skotheim. New York: Cold Spring Harbor Laboratory Press, 2015.