Publications

He Lab publications and preprints

  1. Wei Chen, Victoria Bergstein, Bing He. PI 4-kinases promote cell surface expansion and facilitate tissue morphogenesis during Drosophila cellularization and gastrulation. Preprint: https://www.biorxiv.org/content/10.1101/2022.09.09.507384v1
  2. Melisa A. Fuentes, Hayley N. Piper, Bing He. Dlg1 regulates subcellular distribution of non-muscle myosin II during Drosophila germband extension. Preprint: https://www.biorxiv.org/content/10.1101/2022.08.29.505652v1
  3. Jiayang Chen, Andreia Verissimo, Angela Kull, Bing He. (2023) Early zygotic gene product Dunk interacts with anillin to regulate Myosin II during Drosophila cleavage. Mol Biol Cell mbcE22020046. doi.org/10.1091/mbc.E22-02-0046
  4. Hanqing Guo, Michael Swan, Bing He. (2023) Inhibition of Rho1-mediated actomyosin contractility coupled with measurement of epithelial tension in Drosophila embryos. J Vis Exp 194. dx.doi.org/10.3791/65314-v
  5. Hanqing Guo, Michael Swan, Bing He. (2023) An optogenetic tool to inhibit RhoA in Drosophila embryos. STAR Protoc. 4(1):101972. doi.org/10.1016/j.xpro.2022.101972
  6. Hanqing Guo, Shicheng Huang, Bing He. (2022) Evidence for a role of the lateral ectoderm in Drosophila mesoderm invagination. Front. Cell Dev. Biol. doi: 10.3389/fcell.2022.867438.
  7. Wei Chen, Bing He. (2022) Actomyosin activity-dependent apical targeting of Rab11 vesicles reinforces apical constriction. J Cell Biol. 221(6). doi: 10.1083/jcb.202103069.
  8. Melisa Fuentes, Bing He. (2022) The cell polarity determinant Dlg1 facilitates epithelial invagination by promoting tissue-scale mechanical coordination. Development. 149(6):dev200468. doi: 10.1242/dev.200468.
  9. Hanqing Guo, Michael Swan, Bing He. (2022) Optogenetic inhibition of actomyosin reveals mechanical bistability of the mesoderm epithelium during Drosophila mesoderm invagination. Elife 11:e69082. https://doi.org/10.7554/eLife.69082.
  10. Samuel Reed*, Wei Chen*, Victoria Bergstein, Bing He. (2022) Toll-Dorsal signaling regulates the spatiotemporal dynamics of yolk granule tubulation during Drosophila cleavage. Dev Biol. 481:64-74. doi: 10.1016/j.ydbio.2021.09.009. * These authors contributed equally.

Bing He’s graduate and postdoc work

  1. Bing He*, Adam Martin, Eric Wieschaus. (2016) Flow-dependent myosin recruitment during Drosophila cellularization requires zygotic dunk. Development 143(13):2417-30. * Corresponding author.
  2. Bing He, Konstantin Doubrovinski, Oleg Polyakov, Eric Wieschaus (2014) Apical constriction drives tissue-scale hydrodynamic flow to mediate cell elongation. Nature 508(7496):392-6.
  3. Oleg Polyakov, Bing He, Michael Swan, Joshua Shaevitz, Matthias Kaschube, Eric Wieschaus (2014). Passive mechanical forces control cell shape change during Drosophila ventral furrow formation. Biophys J 107(4):998-1010.
  4. Bing He, Amy Caudy, Lance Parsons, Adam Rosebrock, Attilio Pane, Sandeep
    Raj, Eric Wieschaus (2012) Mapping the pericentric heterochromatin by comparative genomic hybridization analysis and chromosome deletions in Drosophila melanogaster. Genome Res 22(12):2507-19.
  5. Michael Gelbart, Bing He, Adam Martin, Stephan Thiberge, Eric Wieschaus, Matthias Kaschube (2012) Volume conservation principle involved in cell lengthening and nucleus movement during tissue morphogenesis. PNAS 109 (47):19298-303.
  6. Jianglan Liu, Yuting Zhao, Yujie Sun, Bing He, Changsong Yang, Tatyana Svitkina, Yale Goldman, Wei Guo (2012) Exo70 stimulates the Arp2/3 complex for lamellipodia formation and directional cell migration. Curr Biol 22 (16):1510-5.
  7. Bing He and Wei Guo (2009) The exocyst complex in polarized exocytosis. Review. Curr Opin Cell Biol 21(4):537-42.
  8. Xiaoyu Zhang, Kelly Orlando, Bing He, Fengong Xi, Jian Zhang, Allison Zajac, Wei Guo (2008) Membrane association and functional regulation of Sec3 by phospholipids and Cdc42. J Cell Biol 180(1):145-58.
  9. Bing He, Fengong Xi, Xiaoyu Zhang, Jian Zhang, Wei Guo (2007) Exo70 interacts with phospholipids and mediates the targeting of the exocyst to the plasma membrane. The EMBO J 26(24):5167.
  10. Bing He, Fengong Xi, Jian Zhang, Daniel TerBush, Xiaoyu Zhang, Wei Guo (2007) Exo70p mediates the secretion of specific exocytic vesicles at early stages of the cell cycle for polarized cell growth. J Cell Biology 176(6):771-7.