Month: July 2012

Nanoparticle uptake in tumors is mediated by the interplay of vascular and collagen density with interstitial pressure

Nanomedicine. 2013 Feb;9(2):151-8. doi: 10.1016/j.nano.2012.07.002. Epub 2012 Jul 25. ABSTRACT Nanoparticle delivery into solid tumors is affected by vessel density, interstitial fluid pressure (IFP) and collagen, as shown in this article by contrasting the in vivo macroscopic quantitative uptake of 40 nm fluorescent beads in three tumor types.The fluorescence uptake was quantified on individual animals…Continue Reading Nanoparticle uptake in tumors is mediated by the interplay of vascular and collagen density with interstitial pressure