Day: December 25, 2013

Contrast enhanced-magnetic resonance imaging as a surrogate to map verteporfin delivery in photodynamic therapy

J Biomed Opt. 2013 Dec;18(12):120504. doi: 10.1117/1.JBO.18.12.120504. ABSTRACT The use of in vivo contrast-enhanced magnetic resonance (MR) imaging as a surrogate for photosensitizer (verteporfin) dosimetry in photodynamic therapy of pancreas cancer is demonstrated by correlating MR contrast uptake to ex vivo fluorescence images on excised tissue. An orthotopic pancreatic xenograft mouse model was used for…Continue Reading Contrast enhanced-magnetic resonance imaging as a surrogate to map verteporfin delivery in photodynamic therapy