Day: October 26, 2014

Quantitative in vivo immunohistochemistry of epidermal growth factor receptor using a receptor concentration imaging approach

Cancer Res. 2014 Dec 15;74(24):7465-74. doi: 10.1158/0008-5472.CAN-14-0141. Epub 2014 Oct 24. ABSTRACT As receptor-targeted therapeutics become increasingly used in clinical oncology, the ability to quantify protein expression and pharmacokinetics in vivo is imperative to ensure successful individualized treatment plans. Current standards for receptor analysis are performed on extracted tissues. These measurements are static and often…Continue Reading Quantitative in vivo immunohistochemistry of epidermal growth factor receptor using a receptor concentration imaging approach