Boyu Meng, Margaret R. Folaron, Rendall R. Strawbridge, Negar Sadeghipour, Kimberley S. Samkoe, Kenneth Tichauer, Scott C. Davis Proc SPIE Int Soc Opt Eng. 2019 Feb;10874:1087413. doi: 10.1117/12.2510515. Epub 2019 Mar 1. ABSTRACT As the role of immuno-oncological therapeutics expands, the capacity to noninvasively quantify molecular targets and drug-target engagement is increasingly critical to drug development efforts and treatment monitoring. Previously,…Continue Reading Noninvasive imaging of dual-agent uptake in glioma and normal tissue using MRI-coupled fluorescence tomography
Effect of staining temperature on topical dual stain imaging of tissue specimens for tumor identification
Margaret R. Folaron, Rendall R. Strawbridge, Kimberley S. Samkoe, Summer L. Gibbs, Scott C. Davis Proc SPIE Int Soc Opt Eng. 2019 Feb;10862:108620L. doi: 10.1117/12.2509848. Epub 2019 Mar 7. ABSTRACT In the pursuit of reducing re-excision rates in breast conserving surgery, a dual probe specimen staining technique has emerged as a promising approach to identify positive margins during surgery….Continue Reading Effect of staining temperature on topical dual stain imaging of tissue specimens for tumor identification
On the use of fluorescein-based contrast agents as analogs to MRI-gadolinium agents for imaging brain tumors
Scott C. Davis, Margaret R. Folaron, Rendall R. Strawbridge, Caroline E. Filan, Kimberley S. Samkoe, David W. Roberts Proc SPIE Int Soc Opt Eng. 2019 Feb;10862:108620V. doi: 10.1117/12.2510905. Epub 2019 Mar 7. ABSTRACT Magnetic resonance imaging (MRI) of gadolinium (Gd)-based contrast agents plays a central role in managing the treatment of intracranial tumors. These images are involved in diagnosis, surgical…Continue Reading On the use of fluorescein-based contrast agents as analogs to MRI-gadolinium agents for imaging brain tumors