How a ‘pain-o-meter’ could improve treatments

Pain is defined subjectively, but an objective measure of the experience promises to transform its management. Read new article in Nature!

Using functional magnetic resonance imaging, for example, several groups have identified patterns of brain activity that reflect different types of pain — including sensory, emotional and cognitive aspects of the experience. And some researchers have achieved similar results with electrophysiological recordings.

These efforts have yielded some of the most accurate pain-related signatures so far, offering insights into the neural pathways associated with pain and highlighting targets for therapeutic interventions. “This lays the groundwork for identifying potential treatment targets,” says Tor Wager, a neuroscientist at Dartmouth College in Hanover, New Hampshire.

A next-gen pain drug shows promise, but chronic sufferers need more options

About 20 percent of adults in the United States suffer from chronic pain. Scientists hope new research translates into new options for relief. Read new article from ScienceNews here!

“The idea that your brain is actively creating pain, turning it up and down, facilitating spinal cord signaling of pain or dampening it, is really kind of a revelation over the past few decades,” says Wager, of Dartmouth. And it’s an idea that’s just beginning to percolate into mainstream medicine.

Tor Wager featured on CBC Radio’s The Current with Matt Galloway

Listen here! The chronic pain segment begins @ 47:00.

Many Canadians suffer from debilitating chronic back pain, affecting their work, relationships and even mental health. We hear from researchers about a treatment called pain reprocessing therapy, which could offer some sweet relief by re-framing that pain in our minds.

CBC Radio’s The Current is a meeting place of perspectives with a fresh take on issues that affect Canadians today.

Faculty Profile: Tor Wager and Breaking the Neural Code

Tor Wager, the Diana L. Taylor Distinguished Professor in Neuroscience, helps lead Dartmouth’s Breaking the Neural Code academic cluster, which includes research on how placebos affect patients who are feeling pain. “We study how the brain creates mental models, belief structures, that then guide how we experience the world, and in particular how we experience pain,” Wager says.