A step toward developing biological markers of social emotions…

“A Generalizable Multivariate Brain Pattern for Interpersonal Guilt”

In this paper,  we used a predictive modeling approach to identify a whole-brain pattern that is sensitive and specific to the core antecedent of guilt. This signature, while being a distributed pattern across the entire “Emotion” network, exhibits its highest predictive weight in the anterior/middle cingulate cortex and anterior insula. This signature can be used in future studies for detecting guilt- and transgression related neural processes by applying it to harm-based moral decision-making context, or by testing its response in different clinical populations such as those characterized by excessive or reduced experience of guilt (i.e., internalizing disorders versus psychopathy).

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