Study Provides Deep Dive on the Neuroscience of Placebo Effects

Tor Wager, the Diana L. Taylor Distinguished Professor in Neuroscience and co-leader of the Placebo Neuroimaging Consortium discusses a new meta-analysis that gives the most detailed look yet at the neuroscience of placebo effects!  Read more at Dartmouth News

 

fMRI activity during pain is reduced in the areas shown in blue. Many of these are involved in constructing the experience of pain. Activity is increased in the areas shown in red and yellow, which involve the control of cognition and memory. (Image provided by M.Zunhammer et al.)

Continue reading “Study Provides Deep Dive on the Neuroscience of Placebo Effects”

Can providers’ expectations affect patients’ treatment outcomes?

Source: Daily Sun

“Socially transmitted placebo effects” 

Studies of placebo effects have demonstrated that manipulations of the interpersonal and physical treatment context can, in some cases, produce substantial effects on symptoms and behaviour and associated brain processes. Despite the robustness of these interpersonal-expectancy effects, there has been surprisingly little research demonstrating a causal link between providers’ expectations and patients’ treatment outcomes. In this study, we systematically manipulated providers’ expectations in a simulated clinical interaction involving administration of thermal pain and found that patients’ subjective experiences of pain were directly modulated by providers’ expectations of treatment success, as reflected in the patients’ subjective ratings, skin conductance responses and facial expression behaviours. Our study suggests that providers’ expectations about the efficacy of a treatment can substantially affect patients’ treatment outcomes via implicit social cues. This finding has important implications for virtually all clinical interactions between patients and providers and highlights the importance of explicit training in bedside manner when delivering information and interventions.

Continue reading “Can providers’ expectations affect patients’ treatment outcomes?”