Our research focuses on understanding how microbes interact within the human host with a focus on interactions between microbial cells of the same species and from different species. Our studies focus on fungi of the genus Candida, the bacterium Pseudomonas aeruginosa, and the microbes that they interact with in the context of human disease. Our goal is to identify the effects of specific chemical, metabolic and physical interactions as well as to find generalizable themes that drive the evolution of microbes in chronic infections.