Project Title: Targeting the IKK-Binding Domain of NEMO for Inhibitors Discovery Notice of Award: 08/30/2019 Project Period: 09/01/2019 – 07/31/2023 $ 1,476,000
NIGMS R01 Award
Posted in grants
Month: August 2019
The structure of a highly conserved picocyanobacterial protein reveals a Tudor domain with an RNA binding function.
Posted in publication
Bauer KM, Dicovitsky R, Pellegrini M, Zhaxybayeva O, Ragusa MJ
J Biol Chem. 2019 Aug 7. pii: jbc.RA119.007938. doi: 10.1074/jbc.RA119.007938. [Epub ahead of print]
Abstract
Cyanobacteria of the Prochlorococcus and marine Synechococcus genera are the most abundant photosynthetic microbes in the ocean. Intriguingly, the genomes of these bacteria strongly diverge even within each genus, both in gene content and at the amino acid level of the encoded proteins.