The Single Cell Genomics Core has added several exciting new services to its catalogue:
Spatial Transcriptomics
Using the 10x Genomics Visium technology, we can now measure gene expression in the context of tissue specimens. This is a discovery-mode application and requires no a priori knowledge of genes of interest, providing a powerful complement to single cell RNA-seq technologies.
Sample Multiplexing
We leverage barcoded antibody reagents (TotalSeq, BioLegend) as well as lipidated oligos (available in the core) to uniquely barcode individual samples and process in a single reaction on the 10x Chromium platform. This ability to multiplex samples prior to single cell analysis dramatically reduces costs and allows for more robust experimental designs.
Multiomic Analyses
We can now simultaneously generate gene expression as well as chromatin accessibility measurements from the same single cell! This is a powerful application to link regions of the genome with the expression of specific genes, and to identify transcription factor binding motifs likely to mediate this activity.
Visit the SCG Services page for a more complete listing of Single Cell Genomics Core services