Project PI H. Robert Frost graduated from the CQB COBRE in September of 2022 after receiving an R35 MIRA award (R35GM146586, Gene set analysis of single cell genomics). Dr. Frost credits the CQB with providing the critical funding, mentorship and core services needed to advance his independent research and support collaborative projects with other Dartmouth faculty. During his three years with the CQB, his group developed a number of computational methods for the analysis of single cell genomic data and leveraged these methods to analyze single cell data generated in collaboration with Dartmouth immunology researchers and members of the CQB Single Cell and Data Analytics Cores. The protected research time enabled by his COBRE project, along with guidance from his mentors, feedback from the larger CQB group and fantastic core facilities, were instrumental to his success.