Principal Investigator, Single Cell Genomics Core
Drawing from experience in both academia and industry, Dr. Kolling brings a broad range of technical and leadership experience in the field of single cell genomics to facilitate the adoption of these technologies at Dartmouth College. In his 10 years as a researcher, he has gained experience in a range of disciplines at the intersection of single cell genomics, including cell culture and dissociation, Fluorescence Activated Cell Sorting (FACS), Next Generation Sequencing (NGS) and large-scale data analysis techniques. He has also developed a passion for applying these technologies and techniques to a wide array of scientific questions by making them more accessible to researchers everywhere.
Dr. Kolling joined the Genomics and Molecular Biology Shared Resource (GMBSR) at Dartmouth College in 2017 with the goal of leveraging his expertise to advance Next Generation Sequencing capabilities, with a particular focus on single cell genomics. The researchers at Dartmouth College and the Norris Cotton Cancer Center frequently grapple with heterogeneous populations of cells such as those found in a variety of cancers and other immunological malignancies. In the two-and-a-half years since joining the GMBSR, he has lead the implementation of several new workflows, including cost-effective, high-throughput RNA-seq, automated processing as well as single cell DNA and RNA sequencing methodologies. These workflows have opened many new avenues of research at Dartmouth College, supported several publications and spurred new grant applications using these technologies to address some of the most challenging questions in biology today.