What We Do
Biology We explore the operation and control phosphorylation and protein-protein interaction networks, conformational switches, microRNA regulatory pathways, and intracellular trafficking and degradation machineries.
Mentoring We accelerate the research and career trajectories of students, post-docs, and junior faculty members.
Targets We seek new therapeutic targets for brain cancer, colon cancer, pancreatic cancer, airway infection, and inflammation.
Tools We integrate insights from protein biochemistry and engineering, biophysics, high-resolution microscopy, and chemical, structural and computational biology.
Visit Our Successes for a highlighted list of our achievements.
Funding is provided by award P20-GM113132 from the IDeA program of the NIH National Institute of General Medical Sciences, Dartmouth College, the Geisel School of Medicine, the Thayer School of Engineering, and the Norris Cotton Cancer Center.
We also work closely with other IDeA Programs at Dartmouth. These include our COBRE colleagues (the Center for Molecular Epidemiology and the Center for Quantitative Biology) and the NH-INBRE. Our partners across New England include the Vermont Genetics Network, Maine INBRE, and the Center of Integrated Biomedical and Bioengineering Research (CIBBR) from UNH.