bioMT Scientific Cores

bioMT provides two scientific cores which provide state-of-the art equipment, experienced staff, and training to support local and regional researchers. Detailed information can be found on each of Core’s websites.

Download a copy of our Scientific Cores brochure!

Molecular Tools Core and Molecular Interactions & Imaging Core brochure (pdf)

Molecular Tools Core (MTC)

The Molecular Tools Core is a bioMT and Dartmouth community resource that enables research projects via acquisition or production of high quality recombinant proteins. We are developing optimization strategies spanning the molecular, cellular, and process levels in order to build an integrated pipeline capable of producing a wide spectrum of proteins and protein domain fragments.

MTC website

Co-Directors:
Karl Griswold, Ph.D.
Dale Mierke, Ph.D.

Contact:
Andreia Verissimo, Ph.D.
Angela Kull, M.S.


Molecular Interactions & Imaging Core

To quantitatively characterize the molecular interaction of biomolecular systems, the MIIC will provide expertise in the sample preparation (working with the MTC), data collection, and analysis for a range of instrumentation including isothermal calorimetry, surface plasmon resonance, fluorescence-based measurements (fluorescence polarization, alpha-screen), and nuclear magnetic resonance.

MIIC website

Co-Directors:
F. Jon Kull, Ph.D.
Henry Higgs, Ph.D.

Contact:
Zdenek Svindrych, Ph.D.
Andreia Verissimo, Ph.D.,
Angela Kull, M.S.

Microscopy

We provide microscopy support to the bioMT community.  With a broad range of microscopes available at Dartmouth (either located in one of the imaging cores – Class of 1978 Life Sciences Center and Dartmouth-Hitchcock Medical Center, or in individual labs), we can cover many applications. The MIIC uses microscopy for both biochemical and cellular studies, and will help individuals design and implement methodologies to answer specific research questions.

MIIC website

Contact: Zdenek Svindrych, Ph.D.


Dartmouth Chemical Inventory

Database of chemicals at Dartmouth. See “Search Chemical Inventory” under “Quick Links” or under “Chemical Inventory.” Requires Dartmouth NetID and password.