CF researchers can utilize this set of applications, developed by the BBC, to investigate public data and apply novel analyses to both publicly available and user-supplied transcriptomic datasets. Each application offers a point and click interface that delivers analysis results without requiring computational expertise from the user.
Application Name | Link | Description |
ESKAPE Act PLUS | http://scangeo.dartmouth.edu/ESKAPE/ | Streamlined web app for pathway activation analysis of user-provided gene expression data, focusing on ESKAPE pathogens and widely studied prokaryotes. |
HSAPATH | http://scangeo.dartmouth.edu/HSAPath/ | Streamlined web app for pathway activation analysis of user-provided gene expression data, focusing on human cell data. |
CF-Seq | http://scangeo.dartmouth.edu/CFSeq/ | Dynamic dashboard for exploring experimental conditions and gene expression across 120+ CF pathogen studies. |
Rocket-MiR | http://scangeo.dartmouth.edu/RocketmiR/ | Translational launchpad for a new class of miRNA-based antimicrobial therapies that makes cross-species miRNA-mRNA interaction predictions. |
E.PathDash | http://scangeo.dartmouth.edu/EPathDash/ | Dynamic dashboard for rapid reanalysis for Pseudomonas, Staphylococcus, Streptococcus, and Bacteroides RNA-seq datasets that focuses on pathway activation analysis. |
ScanGeo | http://scangeo.dartmouth.edu/ScanGEO/ | Search engine for differentially expressed genes across a collection of NCBI gene expression omnibus (GEO) datasets. |
RESPIRE | http://respire.dartmouth.edu | The RepoSitory for Pulmonary expressIon data ReusE is a unified search interface for publicly available data, where users can download standardized gene expression or microbiome datasets identified based on their search criteria. |