Current Pilot Projects
Project Title: End Stage Kidney Disease in the US Cystic Fibrosis Population
Investigator: Martha Graber, MD, Associate Professor of Medicine
Project Title: Deciphering Mechanisms of Bile Acid Dysmetabolism and Signaling in Cystic Fibrosis
Investigator: Mark Sundrud, PhD, Professor of Medicine
Completed Pilot Projects
Project Title: Mechanism of Kidney Injury in Cystic Fibrosis
Investigator: Sladjana Skopelja-Gardner, PhD, Assistant Professor of Medicine
Mentor: Bruce Stanton, PhD, Professor of Microbiology and Immunology
Project Title: Gut-Lung Axis: Role of Extracellular Vesicles in CF GI Disease
Investigator: Bruce Stanton, PhD, Professor of Microbiology and Immunology
Project Title: Impact of CFTR Modulators on Immune Cell Populations in CF patients
Investigators: Brock Christensen, PhD, Associate Professor of Epidemiology and of Molecular & Systems Biology; Alix Ashare, MD, PhD, Associate Professor of Medicine and of Microbiology & Immunology
Project Title: Tryptophan metabolism by the gut microbiota in cystic fibrosis
Investigator: Benjamin D. Ross, PhD, Assistant Professor of Microbiology and Immunology
Mentor: George O’Toole, PhD, Professor of Microbiology and Immunology
Project Title: Dynamics of bacteriophage infection and resulting bacterial population dynamics within bacterial biofilms
Investigator: Carey Nadell, PhD, Assistant Professor of Biological Sciences
Mentor: Deb Hogan, PhD, Professor of Microbiology and Immunology
Project Title: Effects of potentiators and correctors on microbiome, exacerbation and CFRD in the Dartmouth CF Infants and Children Cohort: children from 7–9
Investigator: Juliette Madan, MD, MS, Associate Professor of Pediatrics and of Epidemiology
Project Title: Development of a stochastic metabolic model for metabolite prediction of gut microbial communities in CF
Investigators: Todd MacKenzie, PhD, Professor of Biomedical Data Sciences and Deb Hogan, PhD, Professor of Microbiology & Immunology
Project Title: Introducing mutations in CFTR into cell lines of the intestine: developing a model for in vitro host-microbe interactions
Investigator: Bryan Luikart, PhD, Department of Molecular and Systems Biology
Project Title: Liver derived hormone hepcidin and its impact on anemia in CF
Investigator: Alex H. Gifford, MD, Associate Professor of Medicine and The Dartmouth Institute