Pilot Projects (P30)

Current Pilot Projects 

 


 

Project Title: End Stage Kidney Disease in the US Cystic Fibrosis Population

Investigator:  Martha Graber, MD,  Associate Professor of Medicine

 


Project Title: Deciphering Mechanisms of Bile Acid Dysmetabolism and Signaling in Cystic Fibrosis

Investigator:  Mark Sundrud, PhD, Professor of Medicine

 


Completed Pilot Projects 


Project Title: Mechanism of Kidney Injury in Cystic Fibrosis

Investigator:  Sladjana Skopelja-Gardner, PhD, Assistant Professor of Medicine
Mentor: Bruce Stanton, PhD, Professor of Microbiology and Immunology

 


 

Project Title: Gut-Lung Axis: Role of Extracellular Vesicles in CF GI Disease

Investigator: Bruce Stanton, PhD, Professor of Microbiology and Immunology

 


 

Project Title: Impact of CFTR Modulators on Immune Cell Populations in CF patients

Investigators: Brock Christensen, PhD, Associate Professor of Epidemiology and of Molecular & Systems Biology; Alix Ashare, MD, PhD, Associate Professor of Medicine and of Microbiology & Immunology

 


 

Project Title: Tryptophan metabolism by the gut microbiota in cystic fibrosis

Investigator: Benjamin D. Ross, PhD, Assistant Professor of Microbiology and Immunology
Mentor: George O’Toole, PhD, Professor of Microbiology and Immunology

 


 

Project Title: Dynamics of bacteriophage infection and resulting bacterial population dynamics within bacterial biofilms

Investigator:  Carey Nadell, PhD, Assistant Professor of Biological Sciences
Mentor: Deb Hogan, PhD, Professor of Microbiology and Immunology

 


 

Project Title: Effects of potentiators and correctors on microbiome, exacerbation and CFRD in the Dartmouth CF Infants and Children Cohort: children from 7–9

Investigator: Juliette Madan, MD, MS, Associate Professor of Pediatrics and of Epidemiology

 


 

Project Title: Development of a stochastic metabolic model for metabolite prediction of gut microbial communities in CF

Investigators: Todd MacKenzie, PhD, Professor of Biomedical Data Sciences and Deb Hogan, PhD, Professor of Microbiology & Immunology

 


 

Project Title: Introducing mutations in CFTR into cell lines of the intestine: developing a model for in vitro host-microbe interactions

Investigator: Bryan Luikart, PhD, Department of Molecular and Systems Biology

 


 

Project Title: Liver derived hormone hepcidin and its impact on anemia in CF

Investigator: Alex H. Gifford, MD, Associate Professor of Medicine and The Dartmouth Institute