Genetic Risk for Alzheimer’s Disease Traced to Links Between Microglial Cells and Amyloid-β Plaques

Audrey Herrald ’23, Medical Sciences, 4/18/2020 Microglia cluster around amyloid-beta plaques in Alzheimer’s Disease; Microglia (red, Iba1 for mouse and CD11b for human) can be found closely associated with amyloid-beta plaques (methoxy, blue) in APP/PS1 mice as well human AD patients (scale bars = 10 μm)[i] Although no single gene … Continue reading