A single cell RNA sequencing data analytics method enhances understanding of the genetic diversity within the tumor microenvironment: CopyKAT utilizes aneuploidy to differentiate healthy cells and cancerous cells

Lord Charité Igirimbabazi, Biological Sciences, Spring 2021 Figure: Shows structural differences between cancer cells and normal cells. Researchers have shown that tumor cells are a mixture of cancer cells and normal cells. Distinguishing malignant cells and nonmalignant cells in the tumor microenvironment is critical for understanding gene expression programs of … Continue reading

Anti-SLAMF7 Treatment for Multiple Myeloma by the Elimination of Immunosuppressive T Cells

Matthew Lutchko ‘23, Biological Sciences, Spring 2021 Figure: Smear preparation of bone marrow from a patient with multiple myeloma, the cancer of plasma cells (Source: Wikimedia Commons). Activated B lymphocytes, or plasma cells, are the only cells capable of secreting antibodies and thus play a critical role in mediating immune … Continue reading